Optimization of a rat lumbar IVD degeneration mannequin for low again ache Introduction: Intervertebral disc (IVD) degeneration is commonly related to low again ache and radiating leg ache. The aim of this examine is to develop a reproducible and standardized preclinical mannequin of painful lumbar IVD degeneration by analysis of structural and behavioral
[IMDRF Essential Principles of Safety and Performance of Medical Devices and IVD Medical Devices Introduction and Consideration] IMDRF revised the Important Ideas of Security and Efficiency of Medical Gadgets and IVD Medical Gadgets (hereinafter known as “EP”), which additional promoted the unification of medical gadget security and effectiveness internationally. As a way to strengthen the scientific evaluate of medical
[Isovaleric acidemia due to compound heterozygous variants of IVD gene in a case] Objective: To analyze the clinical features, biochemical characteristics and molecular pathogenesis of a girl with isovaleric acidemia. Methods: Clinical features, blood spot amino acid profiles and urinary organic acid profiles of the patient were analyzed. Targeted capture, next generation sequencing and
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